Contrave is a prescription combination of naltrexone and bupropion used for chronic weight management in eligible patients. It is not a GLP-1 medication, and suitability depends on medical history, current medicines and contraindications.

How Contrave fits into treatment
Contrave may help some patients with appetite or cravings when combined with nutrition and physical activity. It is taken according to a dose-escalation schedule in the prescribing information and requires follow-up.
- Review blood pressure
- Review seizure history
- Review opioid use or need for opioid pain treatment
- Review eating-disorder and alcohol history
- Check interactions with other medicines
Why an evaluation is required
Contrave is not appropriate for everyone and carries important warnings. Patients should read the current medication guide and promptly report concerning symptoms. Do not share prescription medication.
Comparing non-GLP-1 options
Depending on the patient, a clinician may discuss orlistat, phentermine/topiramate, short-term phentermine or other approaches. Each has distinct benefits, risks and monitoring needs.
Affordable GLP-1 care in Brooklyn
Semaglutide-based options may start at $29.99/week+ and tirzepatide-based options at $45/week+ when insurance is accepted for qualifying visits. Self-pay options may start at $59.99/week+ and $69.99/week+, respectively.
Medical evaluation required. Eligibility, product, dose, pharmacy, availability, visit coverage and total cost vary. Brand-name products and compounded products are not equivalent; compounded drugs are not FDA-approved. Confirm current details before treatment.
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