Metabolic dysfunction-associated steatotic liver disease

W8MD Health Glossary • Greater NYC

Metabolic dysfunction-associated steatotic liver disease, or MASLD, is excess liver fat associated with metabolic risk. It replaces the older term nonalcoholic fatty liver disease in many clinical settings.

Medical evaluation for obesity and metabolic health in New York City
W8MD Weight Loss, Sleep & MedSpa • Brooklyn, New York
Definition

Metabolic dysfunction-associated steatotic liver disease — Metabolic dysfunction-associated steatotic liver disease, or MASLD, is excess liver fat associated with metabolic risk. It replaces the older term nonalcoholic fatty liver disease in many clinical settings.

Why it matters in obesity medicine

Metabolic findings help a clinician estimate risk and choose an appropriate level of care. A single measurement or symptom should be interpreted with the complete medical history.

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Medical disclaimer: This glossary definition is general education, not a diagnosis or individualized treatment recommendation. Do not start, stop or combine medication or supplements without appropriate medical guidance. Call 911 for an emergency. Editorial review: August 2026.